美索巴莫

化合物

美索巴莫(英语:Methocarbamol,商品名:Robaxin等),分子式C11H15NO5,是一种用于短期肌肉骨骼系统疼痛的药物[3][4]

美索巴莫
临床资料
商品名英语Drug nomenclatureRobaxin, Marbaxin, others
AHFS/Drugs.comMonograph
MedlinePlusa682579
核准状况
怀孕分级
给药途径By mouth, intravenous
ATC码
法律规范状态
法律规范
药物动力学数据
药物代谢Liver
生物半衰期1.14–1.24 hours[2]
识别信息
  • (RS)-2-hydroxy-3-(2-methoxyphenoxy)propyl carbamate
CAS号532-03-6  checkY
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard英语CompTox Chemicals Dashboard (EPA)
ECHA InfoCard100.007.751 编辑维基数据链接
化学信息
化学式C11H15NO5
摩尔质量241.24 g·mol−1
3D模型(JSmol英语JSmol
  • O=C(OCC(O)COc1ccccc1OC)N
  • InChI=1S/C11H15NO5/c1-15-9-4-2-3-5-10(9)16-6-8(13)7-17-11(12)14/h2-5,8,13H,6-7H2,1H3,(H2,12,14) checkY
  • Key:GNXFOGHNGIVQEH-UHFFFAOYSA-N checkY

参考文献

编辑
  1. ^ Robaxin-750 - Summary of Product Characteristics (SmPC). (emc). 8 August 2017 [19 April 2020]. (原始内容存档于2021-08-29). 
  2. ^ Sica DA, Comstock TJ, Davis J, Manning L, Powell R, Melikian A, Wright G. Pharmacokinetics and protein binding of methocarbamol in renal insufficiency and normals. European Journal of Clinical Pharmacology. 1990, 39 (2): 193–4. PMID 2253675. S2CID 626920. doi:10.1007/BF00280060. 
  3. ^ Methocarbamol Monograph for Professionals. Drugs.com. American Society of Health-System Pharmacists. [2022-12-11]. (原始内容存档于2021-03-04). 
  4. ^ British national formulary : BNF 76 76. Pharmaceutical Press. 2018: 1093. ISBN 9780857113382. 

外部链接

编辑
  • Methocarbamol. Drug Information Portal. U.S. National Library of Medicine. [2022-12-11]. (原始内容存档于2017-01-23).