鱗狀細胞癌抗原-2

位於18號人類染色體的基因

鱗狀細胞癌抗原-2(英語:Squamous cell carcinoma antigen-2,縮寫SCCA-2SCCA2,也稱為絲胺酸蛋白酶抑制劑家族B亞家族成員4serpin family B member 4,縮寫SERPINB4)是一個人類18號染色體上的基因,編碼一種絲胺酸蛋白酶抑制劑蛋白,是鱗狀細胞癌腫瘤標誌物[5][6][7]

鱗狀細胞癌抗原-2
識別號
別名SERPINB4;, LEUPIN, PI11, SCCA-2, SCCA1, SCCA2, serpin family B member 4
外部IDOMIM600518 MGI2683293 HomoloGene76659 GeneCardsSERPINB4
基因位置(人類
18號染色體
染色體18號染色體[1]
18號染色體
鱗狀細胞癌抗原-2的基因位置
鱗狀細胞癌抗原-2的基因位置
基因座18q21.33起始63,637,259 bp[1]
終止63,644,256 bp[1]
直系同源
物種人類小鼠
Entrez
Ensembl
UniProt
mRNA​序列

​NM_002974
​NM_175041

NM_198680

蛋白序列

NP_002965
​NP_778206

NP_941373

基因位置​(UCSC)Chr 18: 63.64 – 63.64 MbChr 1: 107.08 – 107.21 Mb
PubMed​查找[3][4]
維基資料
檢視/編輯人類檢視/編輯小鼠

參考文獻

編輯
  1. ^ 1.0 1.1 1.2 GRCh38: Ensembl release 89: ENSG00000206073 - Ensembl, May 2017
  2. ^ 2.0 2.1 2.2 GRCm38: Ensembl release 89: ENSMUSG00000073602 - Ensembl, May 2017
  3. ^ Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine. 
  4. ^ Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine. 
  5. ^ Schneider SS, Schick C, Fish KE, Miller E, Pena JC, Treter SD, Hui SM, Silverman GA. A serine proteinase inhibitor locus at 18q21.3 contains a tandem duplication of the human squamous cell carcinoma antigen gene. Proc Natl Acad Sci U S A. May 1995, 92 (8): 3147–51. Bibcode:1995PNAS...92.3147S. PMC 42122 . PMID 7724531. doi:10.1073/pnas.92.8.3147 . 
  6. ^ Sakata Y, Arima K, Takai T, Sakurai W, Masumoto K, Yuyama N, Suminami Y, Kishi F, Yamashita T, Kato T, Ogawa H, Fujimoto K, Matsuo Y, Sugita Y, Izuhara K. The squamous cell carcinoma antigen 2 inhibits the cysteine proteinase activity of a major mite allergen, Der p 1. J Biol Chem. Feb 2004, 279 (7): 5081–7. PMID 14630915. doi:10.1074/jbc.M311585200 . 
  7. ^ Entrez Gene: SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4. [2023-04-10]. (原始內容存檔於2010-12-05). 

外部連結

編輯