甲基马尿酸

甲基马尿酸
别名	Toluric acid; N-(Toluoyl)glycine
识别
CAS号	42013-20-7 ; 27115-49-7; 27115-50-0
PubChem	91637、99223、97479
ChemSpider	82742、89642、87986
SMILES	CC1=CC=CC=C1C(=O)NCC(=O)O; CC1=CC=CC(=C1)C(=O)NCC(=O)O; CC1=CC=C(C=C1)C(=O)NCC(=O)O;
InChI	1S/C10H11NO3/c1-7-4-2-3-5-8(7)10(14)11-6-9(12)13/h2-5H,6H2,1H3,(H,11,14)(H,12,13); 1S/C10H11NO3/c1-7-3-2-4-8(5-7)10(14)11-6-9(12)13/h2-5H,6H2,1H3,(H,11,14)(H,12,13); 1S/C10H11NO3/c1-7-2-4-8(5-3-7)10(14)11-6-9(12)13/h2-5H,6H2,1H3,(H,11,14)(H,12,13);
InChIKey	YOEBAVRJHRCKRE-UHFFFAOYSA-N; YKAKNMHEIJUKEX-UHFFFAOYSA-N; NRSCPTLHWVWLLH-UHFFFAOYSA-N
ChEBI	68455、68500、68552
性质
化学式	C10H11NO3
摩尔质量	193.2 g·mol−1
	若非注明，所有数据均出自标准状态（25 ℃，100 kPa）下。

甲基马尿酸是一种羧酸。甲基马尿酸有三种异构体，包括2-、3-和4-甲基马尿酸。^[1]

甲基马尿酸是二甲苯异构体的代谢产物。^[1]^[2]甲基马尿酸的存在可以用来确定二甲苯的暴露情况，因此它是生物标记。^[2]^[3]

参见编辑

^ ^1.0 ^1.1 HIPPURIC and METHYL HIPPURIC ACIDS in urine (PDF). NIOSH Manual of Analytical Methods (NMAM) Fourth. [2022-12-14]. （原始内容存档 (PDF)于2011-10-20）.
^ ^2.0 ^2.1 Inoue, O.; Seiji, K.; Kawai, T.; Watanabe, T.; Jin, C.; Cai, S. X.; Chen, Z.; Qu, Q. S.; Zhang, T.; Ikeda, M. Excretion of methylhippuric acids in urine of workers exposed to a xylene mixture: Comparison among three xylene isomers and toluene. International Archives of Occupational and Environmental Health. 1993, 64 (7): 533–9. PMID 8482596. S2CID 21534640. doi:10.1007/bf00381104.
^ Kira S. Measurement by gas chromatography of urinary hippuric acid and methylhippuric acid as indices of toluene and xylene exposure. Occupational and Environmental Medicine. 1977, 34 (305–309): 305–309. PMC 1008281  . PMID 588486. doi:10.1136/oem.34.4.305.