勃雄二醇

化合物

勃雄二醇(英語:BolandiolINN,也被称为19-去甲-4-雄烯二醇,19-nor-4-androstenediol,雌甾-4-烯-3β,17β-二醇,estr-4-en-3β,17β-diol,或3β-双氢诺龙,3β-dihydronandrolone)是一种同化類固醇(AAS),从未上市[1]。其二丙酸——二丙酸勃雄二醇酯已上市[1][2]。勃雄二醇与其二丙酸酯除了具有AAS活性外,还具有一定的雌激素孕激素活性[3][4]

勃雄二醇
臨床資料
其他名稱19-Norandrostenediol; 19-Nor-4-androstene-3β,17β-diol; Estr-4-ene-3β,17β-diol; 3β-Dihydronandrolone
识别信息
  • (3S,8R,9S,10R,13S,14S,17S)-13-methyl-1,2,3,6,7,8,9,10,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthrene-3,17-diol
CAS号19793-20-5
PubChem CID
ChemSpider
ChEMBL
CompTox Dashboard英语CompTox Chemicals Dashboard (EPA)
化学信息
化学式C18H28O2
摩尔质量276.42 g·mol−1
3D模型(JSmol英语JSmol
  • O[C@@H]4/C=C2\[C@@H]([C@H]1CC[C@@]3([C@@H](O)CC[C@H]3[C@@H]1CC2)C)CC4
  • InChI=1S/C18H28O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h10,12-17,19-20H,2-9H2,1H3/t12-,13-,14+,15+,16-,17-,18-/m0/s1
  • Key:CMXKUJNZWYTFJN-XFUVECHXSA-N


另见

编辑

参考文献

编辑
  1. ^ 1.0 1.1 J. Elks. The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. 14 November 2014: 899– [2019-06-11]. ISBN 978-1-4757-2085-3. (原始内容存档于2021-02-06). 
  2. ^ Thomas E. Hyde; Marianne S. Gengenbach. Conservative Management of Sports Injuries. Jones & Bartlett Learning. 2007: 1100–. ISBN 978-0-7637-3252-3. 
  3. ^ Hormones: Advances in Research and Application: 2011 Edition. ScholarlyEditions. 9 January 2012: 59– [2019-06-11]. ISBN 978-1-4649-2242-8. (原始内容存档于2021-02-06). 
  4. ^ Attardi, BJ; Page, ST; Hild, SA; Coss, CC; Matsumoto, AM. Mechanism of action of bolandiol (19-nortestosterone-3beta,17beta-diol), a unique anabolic steroid with androgenic, estrogenic, and progestational activities. The Journal of Steroid Biochemistry and Molecular Biology. 2010, 118 (3): 151–61. PMC 2831543 . PMID 19941958. doi:10.1016/j.jsbmb.2009.11.008.